What is GW0742
GW0742 is a relatively new product, and there is little information about it at present.
However, you must be familiar with GW501516. GW0742 is called super GW501516. They are very similar in molecular interface, with only one difference of F yard. they were jointly invented by Ligand Pharmaceuticals and GlaxoSmithKline (GSK). At present, GSK is still developing a variety of derivative products with GW0742 as the core structure.
GW0742, also known as GW610742, is a PPAR δ/β Receptor agonists, in addition to activating PPAR δ/β In vitro, it has been proved to have weak effects on other receptors, such as thyroid.
PPAR β/δ Ligands are members of a group of nuclear receptors that play different roles in metabolism, development and cell differentiation, and have many effects on genes involved in metabolism.
PPAR δ It regulates cell metabolism, energy balance, fatty acid intake, insulin secretion and sensitivity – basically reprogramming muscle fibers to enhance endurance and decompose fat.
GW0742 shows the metabolic changes of peripheral lymphoid tissues by increasing the expression of fatty acid oxidation genes during exercise. It also reduces visceral adipose tissue mass and skeletal muscle inflammation, increases endurance and insulin sensitivity. This means that it provides a β/δ Access to treatment methods to improve the treatment of obesity.
The selectivity of GW0742 is 1000 times that of other human PPAR subtypes.
What is GW0742 benefits
GW0742 has many medical benefits, such as improving insulin sensitivity, reducing body inflammation, protecting blood vessels, increasing cartilage composition, and reducing total cholesterol. The most concerned part of bodybuilder, also has many benefits.
- Accelerate fat burning
In some cases, the body stores fat and uses muscles for energy. But GW0742 can maintain muscle tissue while burning fat as a source of energy for the body. For women who want to shape, It can also burn fat in the arms, legs and abdomen, which are the most difficult parts of the body to reduce fat. Increase muscle — GW0742 affects the process of muscle production rate, and in the case of muscle damage, the rate of complete regeneration is twice that of the original.
- Improve muscle endurance
GW0742 increases the number of mitochondria in muscle tissue. High concentration of mitochondria can improve the efficiency of metabolic process, thus producing more ATP It increases the intensity of muscle contraction and prolongs the maximum time of aerobic exercise. Therefore, it is suitable for long-distance running, cycling and other activities. For the bodybuilder, after exercise, people usually feel exhausted and sleepy. It inhibits glucose metabolism, while the body passively starts to burn fat to provide energy for exercise, which will not make people feel exhausted after exercise.Improving endurance means training longer, burning more calories, and getting a sharper muscle appearance.
GW0742 dose
Most body builders usually have a dose of 10mg/day, and the maximum dose does not exceed 25mg
It does not mean that 10g is the starting dose. Each person’s tolerance is different, and their weight base is also different. There will be differences between doses.
It is usually taken orally directly, or it can be dissolved before use.
GW0742 half-life
The half-life of GW0742 is slightly shorter than that of GW501516, which is about 12H. You can use it once a day. Some bodybuilders choose to use it twice a day.
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